门诊高血压患者用药情况调查分析

Analysis of drug use of out patients with hypertension

目的探讨我院门诊高血压药物的应用现状和趋势。方法调查分析我院门诊就医的高血压患者治疗药物处方7 920张,分析抗高血压药物的使用情况及治疗方案,监测药物使用的合理性。结果我院门诊最常用的降压药有7类20个品种,其中钙拮抗剂(CCB)占35%、β-受体阻滞剂占21%、血管紧张素转化酶抑制剂(ACEI)占18%、血管紧张素Ⅱ受体拮抗剂(ARB)占13%、利尿剂占9%、复方制剂占3%和中药制剂占1%;单种药物治疗占46.2%,联用2种或2种以上药物治疗占53.8%。硝苯地平缓释片(14.27%)、贝那普利(11.7%)和美托洛尔(11.4%)在同类药物中使用率最高。结论我院门诊抗高血压药物应用种类及降压治疗方案基本符合中国高血压防治指南及个体化治疗方案,应用长效抗高血压药物制剂及合理的联合用药是当今高血压治疗的主流。

Objective To investigate the status and trends of our hospital′s hypertension drugs application.Methods 7 920 prescriptions of hypertension out patients were analyzed.Results The most commonly used antihypertensive drugs in our hospital were seven classes and 20 varieties,in which the calcium channel blocker（CCB）accounted for 35%,β-blockers 21%,angiotensin Ⅱ-converting enzyme inhibitors（ACEI）18%,angiotensin Ⅱ receptor blocker（ARB）13%,diuretics 9%,compound preparations3% and traditional Chinese medicines 1%;Single-drug therapy accounted for 46.2%,combined with two or more kinds of drugs53.8%.Extended Release Nifedipine Tablets（14.27%）,benazepril（11.7%）,and metoprolol（11.4%）had the highest utilization rate in the same drug class.Conclusion Our hospital antihypertensive drug application types and antihypertensive treatment programs were in line with Chinese Hypertension Prevention Guide.Individualized treatment programs,long-acting anti-hypertensive drugs and rational drug combination formulation are the developing trend in the treatment of hypertension.