推拿背腰部膀胱经穴对慢性疲劳综合征IFN-γ、TNF-α含量的影响

Effect of Back Waist Bladder Merdian Massage on the Contents of INF-γ,TNF-α in Patients with Chronic Fatigue Sydrome

目的观察推拿背腰部膀胱经对慢性疲劳综合征患者血清IFN-γ、TNF-α含量的调节及临床疗效。方法选择符合美国疾病控制与预防中心1994年修订的CFS诊断标准的患者60例,随机分为推拿组、针刺组,每组30例,分别采用推拿背腰部膀胱经法治疗(推拿组)、针刺背俞穴法治疗(针刺组),观察两组患者治疗前后FS-14、SAS、DSI的评定分值及血清IFN-γ、TNF-α含量的变化。结果两组CFS患者经过不同方法治疗后生活质量均较治疗前提高,差异有统计学意义(P<0.05,P<0.01);推拿组在改善CFS患者临床症状和健康状况、缓解疲劳及提高临床疗效方面优于单纯针刺法(P<0.05),治疗前后比较差异具有统计学意义(P<0.01)。结论推拿背腰部膀胱经对CFS患者有一定的治疗作用,其机理可能与降低血清的IFN-γ、TNF-α含量有关。

Objective To observe the effect of back waist bladder meridian massage on the contents of IFN - γ and TNF - α in patients with chronic fatigue syndrome（CFS）. Method 60 cases of CFS patients were randomly divid- ed into massage group and acupuncture group ,30 cases in each group, massage group received back waist bladder merid- ian massage,acupuncture group received shenshu point back acupunture, observe the FS - 14, SAS, DSI evaluation scores and serum levels of IFN -γ and TNF - α of both groups before and after treatment. Results After treatment,the life quality of both group improved with statistical significance （ P 〈 0.05 ） ; massage group was better in improving the clinical symptoms and health conditions for patients with CFS, the effect of relieving fatigue and improving the thera- peutic effects was more obvious than acupuncture group （P 〈 0. 01 ）. Conclusion Back waist bladder meridian mas- sage has a certain efficacy on CFS, its mechanism may be related to the reduction of serum IFN - γ, TNF - α contents in CFS patients.