天然药物抗氧化活性物质研究进展

Recent progress on antioxidant products from natural sources

氧化胁迫与衰老和多种疾病的发生发展密切相关,许多抗氧化剂具有延缓衰老和防治氧化胁迫相关疾病的活性。其中,植物来源的天然抗氧化剂还具有来源可靠、安全性高、副作用低等诸多优点,是目前药品、保健品、化妆品等行业的重要开发对象。本文重点介绍了天然药物抗氧化活性物质的国内外研究进展,同时简单介绍了目前开发抗氧化剂常用的体内外活性评价方法,并对这些天然抗氧化物质在生物医药领域的应用前景进行了展望。

Oxidative stress is closely associated with ageing and ageing-related diseases.Recent studies suggest that antioxidants can delay ageing process and prevent oxidative stress-related diseases.Natural antioxidants from plants and other sources have a variety of advantages such as source authenticity, high safety and low side effect,and thus have great potentials in pharmaceutical,health and cosmetic products.This paper provides an overview of recent progress on natural antioxidant products.Commonly used evaluation methods on antioxidant activities,including both in vitro and in vivo assays,as well as application prospects of natural antioxidant products in biomedical field,are also briefly introduced.