超声造影后颈部淋巴结粗针与细针穿刺活检的结果比较

Comparative study of core needle biopsy and fine needle aspiration cytology in the diagnosis of neck lymph node diseases with contrast-enhanced ultrasound

目的 探讨超声造影后颈部淋巴结粗针与细针穿刺活检的优劣势.方法 用掷硬币法将患者随机分为A、B两组,均于穿刺术前超声造影后选择目标淋巴结及穿刺点,A组行粗针穿刺活检,取出组织用10％甲醛固定;B组行细针穿刺活检,取出物涂片后95％乙醇固定,两组均送病理学检查.结果 A组：49枚颈部淋巴结肉眼取材成功率100.0％,病理诊断阳性率97.9％;B组：56枚颈部淋巴结肉眼取材成功率96.4％,病理诊断阳性率82.1％;A组病理诊断阳性率较B组高（χ^2=6.97,P＜0.05）.结论 超声造影后颈部淋巴结粗针穿刺活检病理诊断阳性率较细针高.

Objective To compare the efficacies of core needle biopsy and fine needle aspiration cytology in the diagnosis of neck lymph node diseases with contrast-enhanced ultrasound. Methods A total of 105 patients with enlargement cervical lymph nodes were randomly divided into two groups, 49 in group A and 56 in group B. All patients were firstly examined with contrast-enhanced ultrasound to determine the targeted lymph node and the puncture point. Core needle biopsy was performed in Group A and tissues were fixed by with 10% formaldehyde; Fine needle aspiration cytology was performed in Group B and extracts were smeared and fixed with 95% alcohol. Results The success rates of sampling were 100. 0% in group A and 96. 4% in group B. The positive rates of pathological examinations were 97.9% in group A ; and 82. 1% in group B, with a significant difference between two groups （χ^2= 6. 97, P 〈 0. 05 ）. Conclusion The pathologically positive rates of core needle biopsy is higher than that of fine needle aspiration cytology for the diagnosis of neck lymph node diseases with contrast-enhanced ultrasound.