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中国传统廉政文化局限性探析 被引量:5

The Influence of Dahuang Zhechong Bolus on Lewis Lung Cancer Mice
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摘要 中国传统廉政文化是农耕社会的产物,而农耕社会的自然经济基础和宗法血缘关系的社会条件,必然促使传统廉政文化带来了诸多局限性。产生于宗法制度基础上的中国传统廉政文化以服务于封建君主专制为宗旨,因而它无法改变中国封建社会贪贿成风的局面,也无力挽救中国封建社会必然灭亡的命运。中国传统廉政文化只有与时俱进才能焕发出其崭新的生命力。 Objective:To study the influence of Dahuang Zhechong pills on Lewis lung cancer mice. Method:64 SPF Kunming mice, half male and half female,were randomly divided into 4 groups:blank group, model group,TCM group and western medicine group. Blank group receives no medicine,as for other 3 groups,every mouse was injected 0.2 ml Lewis lung cancer cell suspension at the right maxillary,and began the medical interference 3 days after the modeling. On the 29th day,the mice were weighed;the tumors and spleens were cut and weighed,tumor inhibition rate,thymus index and spleen index were calculated. Serum interleukin2 (IL-2)was tested with ELISA. The rate of CD4+CD25+Foxp3+ in CD4+ was tested with flow eytometer. Result: ①Tumor inhibition of TCM group was 44.73% ,and that of the western medicine group was 48.82%. ②The effect on organ index:compared with the model group, the thymus index of the TCM group was increased(P〈0.05);the spleen indice of the TCM group and the western medicine group were decreased(P〈0.05 ), and the TCM group decreased obviously slower than that of the western medicine group(P〈0.05). ③the effect on the proportion of CD4+CD25+Foxp3+ in CD4+ and IL-2 level in sernm:compared with the blank group,the proportion of CD4+CD25+Foxp3+ T-reg in CD4~ T-reg was increased obviously in model group (P〈0.01). Compared with the model group ,the proportion of CD4+CD25+Foxp3+T-reg in CD4+ T-reg in the spleen of the TCM group and the western medicine group were decreased (P〈0.05). The IL-21evel serum:compared with the blank group,the IL-2 level in the serum of the model group,the TCM group and the western medicine group decreased obviously(P〈0.05). Compared with the modeling group,the IL-2 level in serum of the TCM group was increased obviously (P〈0.05),while for the western medicine group, the IL-2 level in serum was decreased (P〈0.05).Conclusion:Dahuang Zhechong pills can affect the immune statue of Lewis lung cancer mice.Its tumor inhibition mechanism may relate to the expression lowering of CD4 +CD25 +Foxp3 + and the serum IL-2 level. DahuangZhechong Bolus has the function of tumor inhibition,at the same time it can protect the immune organ of Lewis lung cancer mice and promote the immune function of the mice.
作者 赵瑞宝 曹慧慧 张瑞卿 郭晓峰 李俊莲 Zhao Ruibao, Cao Huihui,Zhang Ruiqing, Guo Xiaofeng,Li Junlian ( Shanxi College of TCM, Taiyuan Shanxi 030024)
机构地区 山西中医学院
出处 《山西中医学院学报》 2016年第3期13-16,共4页 Journal of Shanxi College of Traditional Chinese Medicine
关键词 中国传统廉政文化 局限性 服务 封建君主专制 Dahuang Zhechong pills Lewis lung cancer immune
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