广东不孕妇女和捐精人群TORCH感染季节分布回顾性分析

Retrospective analysis of TORCH infection in infertile women and sperm donors

目的探讨广东地区不孕症及拟捐精人群TORCH感染率及不同季节TORCH感染分布情况。方法 选取2012年1月~2015年6月来我院就诊的10 531例不孕症妇女及1505例拟捐精男性的TORCH Ig M抗体的检测结果进行回顾性分析。结果 广东地区不孕症妇女TORCH Ig M抗体阳性率从高至低分别是巨细胞病毒（1.7%）、单纯疱疹病毒（1.1%）、风疹病毒（1.1%）及弓形虫（0.7%）。拟捐精男性TORCH Ig M抗体阳性率从高至低分别是巨细胞病毒（1.8%）、单纯疱疹病毒（1.3%）、风疹病毒（1.5%）及弓形虫（0.9%）。其中巨细胞病毒阳性率最高,而弓形虫阳性率最低,TORCH总阳性率4.7%（563/12 036）。本研究中TORCH感染在四季均可发生,差异无统计学意义（P〉0.05）。结论 广东地区人群中存在一定比例的TORCH感染,感染无明显季节变化,要广泛地进行卫生宣传教育,重视TORCH早期筛查,减少不良妊娠的发生。

Objective To investigate the TORCH infection rate of infertile women and sperm donors in Guangdong area and the TORCH infection distribution in different seasons.Methods From January 2012 to June 2015, 10 531 cases of infertiled women and 1505 sperm donors were detected by enzyme linked immunosorbent assay （ELISA） for the detection of Toxoplasma,rubella virus,cytomegalovirus and herpes simplex virus IgM antibody in our hospital.Results From high to low,the positive rate of IgM TORCH antibody in infertiled women in Guangdong area was 1.7% in Cytomegalovirus, 1.1% in Herpes simplex virus, 1.1% in Rubella virus and 0.7% in Toxoplasma gondii,respectively.From high to low,the positive rate of IgM TORCH antibody in sperm donors was 1.8% in Cytomegalovirus, 1.3% in Herpes simplex virus, l.5% in Rubella virus and 0.9% in Toxoplasma gondii,respectively.There was no significance in same pathgoen between infertile women and sperm donors,the positive rate of CMV was the highest and the positive rate of Toxoplasma gondii was the lowest.The total positive rate was 4.7%（563/12 036）.In different seasons,the positive rate of pathgoen has no significance difference （P〉0.05）.Conclusion There is a certain proportion of TORCH infection in the infertile population with no obvious seasonal changes,which should be widely used in health education to reduce the incidence of adverse pregnancy induced by TORCH infection.