瓜蒌皮注射液对急性心肌梗死患者住院期间心脏不良事件影响

Clinical Observation of Gualoupi Injection's Influence During ho Spitalization after Acute Myocardial Infarction

目的:观察内科保守治疗联合瓜蒌皮注射液对急性心肌梗死住院期间心脏不良事件发生率及其安全性的影响。方法:选取急性心肌梗死且选择内科保守治疗的患者140例,随机分为治疗组70例给予内科常规药物治疗联合瓜蒌皮注射液,对照组70例给予西医内科常规药物治疗,疗程为2周,观察2组在院期间心脏不良事件发生率及其安全性。结果:治疗组发生心脏不良事件的几率为12.9%,对照组发生心脏不良事件的几率为27.1%,2组差异有统计学意义(P<0.05);治疗组发生出血事件的比例为28.6%,对照组发生出血事件的比例为25.7%,2组差异无统计学意义(P>0.05)。结论:瓜蒌皮注射液可以降低急性心肌梗死在院期间心脏不良事件的发生率,且不增加出血的风险。

Objective： To observed the influence of the internal conservative treatment combined with Gualoupi Injection on the major adverse cardiac events during hospitalization after acute myocardial infarction. Methods： Selected 140 cases of patients with acute myocardial infarction and chose medicine conservative treatment, randomly divided into two groups as treatment group and control group, every group with 70 cases.Treatment group were given conventional western medicine plus Gualoupi Injection, while the control group only received conventional western medicine, treatment course was 2 weeks.To observe the incidence of major adverse cardiac events and safety of related vessels in the two groups during hospitalization. Results： The incidence of major adverse cardiac events of treatment group was 12.9%, and the control group was 27.1%, the difference between the 2 groups was statistically significant（P〈0.05） The incidence of bleeding in the treatment group was 28.6%, and the control group was 25.7%, the difference was not statistically significant（P〉0.05）. Conclusion： Gualoupi Injection can reduce the incidence of major adverse cardiac events after acute myocardial infarction, and doesn＇t increase the risk of bleeding.