脾脏炎性假瘤样滤泡树突细胞瘤的CT表现及文献复习

CT findings of inflammatory pseudotumor- like FDC tumor and literature review

目的:研究脾脏炎性假瘤样滤泡树突细胞瘤的CT表现及病理学特征。方法:回顾性分析2例经手术和病理证实为炎性假瘤样滤泡树突细胞瘤的临床特点、CT表现及病理资料,并复习相关文献,总结炎性假瘤样滤泡树突细胞瘤的CT及病理学特征。结果:2例炎性假瘤样滤泡树突细胞瘤CT平扫表现为类圆形低密度肿块影,边界清晰,密度均匀,增强扫描动脉期示病灶边缘强化,门脉期病灶呈渐进性持续强化并向中央填充。病理:炎性假瘤样滤泡树突细胞瘤除了梭形细胞和炎细胞外,还有由少许多核巨细胞和组织细胞构成的伴有中心坏死的肉芽肿样改变;EBER原位杂交:EBER-ISH(+)。结论:脾脏炎性假瘤样滤泡树突细胞瘤CT动态增强扫描具有渐进性、持续性强化的特点,其CT表现与部分脾脏炎性假瘤相似,确诊需镜检及免疫组织化学检查。

Objective： To investigate the CT and cl inical pathological features of inflammatory pseudotumor - l ike FDC tumor. Methods ： The cl inical , CT and pathological data of 2 cases of inflammatory pseudotumor - l ike FDC tumor were retrospectively analyzed. The clinical and pathological data of cases were confirmed by surgery and pathology.Results ：Two cases of inflammatory pseudotumor - l ike FDC tumor CT scan showed that the shape of circular low den-sity mass, clear boundary, uniform density, enhanced scanning arterial phase can enhance the edge of the lesion, the portal phase focus was gradually increased, and to the central filling. Pathology ： In addition to spindle cells and in f lam -matory cells,the tumor was composed of a small number of nuclear giant cells and tissue cells with central necrosis, and the EBER - ISH（ ＋） . EBER in situ hybridization ：EBER - ISH （＋）. Conclusion： The dynamic enhanced CT scan of the spleen inflammatory pseudotumor - like FDC tumor has a progressive and continuous enhancement. The CT findings were similar to that of some of the inflammatory pseudotumor - like FDC tumor.