血栓弹力图参数与脓毒血症抗感染无效的相关性分析

Correlation Analysis of Thrombelastogram Parameters and Anti Infection Sepsis Invalid

目的探讨血栓弹力图(Thrombelastograph,TEG)参数对脓毒血症抗感染治疗效果的评估价值。方法按照脓毒血症患者病情严重程度进行分组,比较抗感染效果与TEG参数及炎症指标降钙素原(procalcitonin,PCT)的相关性。结果抗感染无效与TEG参数、PCT均存在相关性,即随着病情严重程度的增加,R和K增大,MA和a减小;PCT增大。结论脓毒血症常规抗感染治疗无效与凝血功能障碍可能存在密切相关性,TEG参数对抗感染效果评估有一定参考价值。

Objective To explore the value of evaluation of Thrombelastogram（ Thrombelastograph,TEG） parameters on sepsis anti infection treatment effect. Methods Patients with Sepsis were grouped according to the severity of the disease,to com-pare the anti calcitonin effect and TEG parameters and inflammatory markers in infection factor procalcitonin（ PCT） correlation. The correlation of anti infection effect with TEG parameters and inflammation index（ procalcitonin,PCT） was compared. Results Anti infection ineffective were correlated with TEG parameters,PCT,that was,with the increase of the severity of the disease,K and R increased,MA and a decreased,PCT increased. Conclusion Conventional anti infection treatment of sepsis ineffective and coagu-lation dysfunction may exist close correlation,and the TEG parameter on evaluation of anti infection effect has a certain reference value.