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胰岛β细胞基因突变致低血糖伴高血糖综合征的临床识别及处理

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摘要 自1981年Aynsley-Gren等首次报道PHHI以来，后续学者对其遗传背景做了大量和深入的研究，清楚一些，还有相当一些还不算清楚。PHHI至今还是一种极少见的遗传性疾病，使胰岛β细胞持续不适当分泌胰岛素是PHHI的病理生理基础。
作者 于婉 刘国良 曹翠苹
机构地区 中国医科大学盛京医院 中国医科大学第一附属医院
出处 《实用糖尿病杂志》 2016年第4期9-11,共3页 Journal of Practical Diabetology
关键词 胰岛Β细胞 磺脲类受体(SUR1) KATP通道基因 钾离子通道基因Kir6.2(KCNJⅡ)葡萄糖激酶基因 青少年的成年发病型糖尿病(MODY) 低血糖 高胰岛素血症
分类号 R587 [医药卫生—内分泌]
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参考文献15

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二级参考文献27

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实用糖尿病杂志
2016年 第4期

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