铁超载与非酒精性脂肪性肝病的关系及其作用机制的研究进展

Relationship between iron overload and nonalcoholic fatty liver disease: An update

作为多重打击的一部分,铁超载在非酒精性脂肪性肝病(nonalcoholic fatty liver disease,N A F L D)的发生发展过程中起到重要作用.铁超载影响机体的糖、脂、能量代谢以及炎症反应.因此本文就铁超载与NAFLD的关系加以综述,以期能阐明铁超载对NAFLD的代谢调节机制.

As a component of the multiple hits, iron overload plays an important role in the development of nonalcoholic fatty liver disease（NAFLD）. Iron overload could affect glucose, lipid, energy metabolism and inflammatory reaction. This paper reviews the relationship between iron overload and nonalcoholic fatty liver disease, in order to clarify how and why iron overload influences the progression of NAFLD.