龙附方治疗慢性前列腺炎/慢性盆腔疼痛综合征疗效观察

Observation of Effect of Longfu Formula on Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome

目的:观察龙附方治疗经临床表型分类系统(UPOINT)分类的慢性前列腺炎/慢性盆腔疼痛综合征(CP/CPPS)的临床疗效。方法:经UPOINT分类确诊的CP/CPPS患者100例,使用中药协定方龙附方进行治疗12周,在治疗前、治疗后6周、治疗后12周对患者进行国立卫生研究院慢性前列腺炎症状指数(NIH-CPSI)评分并记录不良反应情况,分析UPOINT因子与经龙附方治疗后NIH-CPSI评分下降的相关性,疗效评定标准为有效和无效。结果:本组治疗后有效75例,无效20例,总有效率78.95%(75/95);U因子、O因子、T因子与经龙附方治疗后患者的NIH-CPSI评分的下降均有关(P<0.01)。结论 :龙附方治疗U因子、O因子、T因子阳性的CP/CPPS效果安全有效。

Objective：To observe the clinical effect of Longfu formula on the treatment of chronic prostatitis/ chronic pelvic pain syndrome（CP/CPPS） which were classified by the urinary,psychosocial,organ-specific,in- fection,neurologic/systemic,tenderness （UPOINT） system. Methods：A total of 100 patients diagnosed as CP/ CPPS were enrolled in this study. All patients were classified by the UPOINT system and underwent a 12-week therapy of Longfu formula. The national institutes of health-chronic prostatitis symptom index （NH-CPSI） and adverse events of the patients were evaluated before treatment,6 weeks after treatment and 12 weeks after treatment respectively. The correlation between UPOINT factors and the decrease of NIH-CP- SI after treatment by Longfu formula was analyzed. According to the assessment criteria,the clinical result was either effective or ineffective. Results：The Longfu formula was effective on 75 patients and ineffective on 20 cases. The total ,effective rate was 78.95%（75/95）. The factor of U,O,T were correlated with the de- crease of NIH-CPSI （P〈 0.01）. Conclusion：Longfu formula is safe and effective on CP/CPPS of which the U, O,T factor was positive.