原发性瘢痕性脱发发病机制和治疗研究进展

Updates on the Pathogenesis and Management of Primary Cicatricial Alopecia

原发性瘢痕性脱发(PCA)是一组以毛囊为中心、受到永久性和炎症性破坏为特征的脱发性疾病,早期诊断和积极治疗对于进展期的PCA有着至关重要的意义。明确PCA的发病机制将有利于开发保护毛囊避免受到炎症破坏的药物,从而有效治疗PCA。

Primary cicatricial alopecia（ PCA） include a group of disorders characterized by permanent destruction of the hair follicle and irreversible hair loss caused by inflammatory infiltration,an early diagnosis and an aggressive treatment in the case of active hair loss are crucial in the management of PCA. Understanding the pathogenesis pathogenesis of PCA may facilitate the development of novel protective strategies againstdestruction of epithelial tissue in PCA.