经尿道钬激光前列腺剜除术治疗良性前列腺增生40例效果观察

Clinical Effect of Holmium Laser Enucleation of the Prostate in the Treatment of 40 Patients with Benign Prostatic Hyperplasia

目的:观察经尿道钬激光前列腺剜除术治疗良性前列腺增生的安全性及疗效。方法:对我院2015年1月至2015年7月收治的40例良性前列腺增生患者行经尿道钬激光前列腺剜除术,对术中、术后手术并发症进行统计,并对术前及术后3个月的最大尿流率(peak urinary flow rate,Qmax)、残余尿量(residual urine volume,PVR)、国际前列腺症状评分(International Prostate Symptom Score,IPSS)、生活质量评分(quality-of-life,QOL)等随访资料进行对比研究。结果:术后失访6例,纳入34例。患者术后3个月Qmax、PVR、IPSS及QOL较术前有明显改善(P<0.01)。术中膀胱损伤1例,术后压力性尿失禁2例,尿道外口狭窄1例,所有患者未出现TUR综合征,无术中、术后严重出血需输血者。结论:该手术方式疗效良好、适应证广泛、安全性较高、风险较小,值得在基层医院推广应用。

Objective：To evaluate the safety and clinical effect of holmium laser enucleation of the prostate （HoLEP） for pati-ents with benign prostatic hyperplasia （BPH） .Methods：A total of 40 patients with BPH from Jan 2015 to Jul 2015 were underwent HoLEP.Pre-and postoperative complication were recorded and the differences of the clinical parameters were also compared, including peak urinary flow rate （Qmax）, residual urine volume （PVR）, International Prostate Symptom Score （IPSS）, quality-of-life （QOL） .Results：A total of 34 patients were included after operation and 6 patients lost to follow-up. Qmax, PVR, IPSS, QOL after three months postoperatively were improved significantly compared with that of preoperative （P〈0.01） .Complications included intraoperative bladder injury （1 case）, postoperative stress incontinence （2 cases）, urethral stricture （1 case） .No patients experienced the sign of TUR syndrome and blood transfusion for severe bleeding.Conclusion：HoLEP has the advantage of good therapeutic effects,wide scope of application,better safety performance,smaller risk and it’s worth popularizing in primary hospitals.