糖皮质激素辅助阿奇霉素治疗儿童支原体肺炎

Treatment of infantile mycoplasma pneumonia by Glucocorticoids assisted with Azithromycin

目的观察糖皮质激素辅助治疗儿童支原体肺炎的临床疗效。方法选取2014年9月-2015年11月在信阳市第一人民医院住院治疗的96例支原体肺炎患儿,将其分为阿奇霉素治疗对照组和阿奇霉素联合糖皮质激素治疗观察组,观察组在给予阿奇霉素基础上静滴地塞米松0.25 mg/（kg·d）,体温正常后改用口服泼尼松片0.5~1.0 mg/（kg·d）,后逐渐减量,治疗1周后比较两组患儿的临床疗效。结果观察组痊愈率明显高于对照组,同时观察组咳嗽消失时间、退热时间以及肺部阴影消失时间,与对照组相比明显缩短,差异有统计学意义（P〈0.05）。结论糖皮质激素联合阿奇霉素可有效缓解支原体肺炎患儿的临床症状。

Objective To evaluate the clinical efficacy of glueocortieoids combined with Azithromycin in the treatment of infantile mycoplasma pneumonia. Methods Ninty-six children with mycoplasma pneumo- nia in our hospital from Sept. 2014 to Nov. 2015 were chosen and divided into two groups, one treated by Azithromycin as control groups and by glucocorticoids combined with Azithromycin as observation groups. In the observation groups dexamethasone 0.25 mg/（kg＇d） was given until the body temperature returned to normal, and then maintained with prednisone 0.5-1.0 mg/（kg·d） for a treatment course of a week. Results The curative rate in observation groups was significant higher than that in the control group. The duration of cough, fever and lung X-ray shadow existance were also significantly reduced in the observation group than those in the control group （P〈0.05）. Conclusion In the treatment of mycoplasma pneumonia, glucocorticoid combined with azithromycin could relieve symptoms in children with mycoplasma pneumonia.