吸入麻醉药与术后认知功能障碍被引量：6

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摘要术后认知功能障碍（postoperative cognitive disfunction,POCD）是手术和麻醉后产生的认知功能损害,是一种短暂的记忆力、注意力、语言理解力和社会整合能力的功能紊乱,可发生在任何年龄,但多见于老年人。国际POCD研究小组研究表明,年龄〉60岁行非心脏手术治疗患者术后1周POCD发生率高达40%,术后3个月仍有10%,主要表现是记忆受损。

作者郄晓娟郑文婧郝立净徐贯杰

机构地区河北医科大学第三医院麻醉科哈励逊国际和平医院麻醉科

出处《河北医科大学学报》 CAS 2016年第8期989-992,共4页 Journal of Hebei Medical University

基金河北省医学科学研究重点课题(ZL20140225)

关键词麻醉药吸入认知障碍综述文献

分类号 R614.21 [医药卫生—麻醉学]

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1Monk TG, Weldon BC, Garvan CW, et al. Predictors of cognitive dysfunction after major noncardiac surgery [J]. Anesthesiology, 2008,108 ( 1 ) : 18-- 30.
2Gross AF, Stern TA. Neuropsychiatric conditions associated with anesthesia exposure [J]. Psychosomatics, 2014, 55 ( 1 ) 21--28.
3Fontes MT, McDonagh DL, Phillips-Bute B, et al. Arterial hyperoxia during cardiopulmonary bypass and postoperative cognitive dysfunction[J].J Cardiothorac Vasc Anesth, 2014, 28(3):462--466.
4Lu SM,Gui B,Dong HQ,et al. Prophylactic lithium alleviates splenectomy-induced cognitive dysfunction possibly by inhibiting hippocampal TLR4 activation in aged rats[J]. Brain Res Bull, 2015,114 : 31 --41.
5孙海军,梁淑娟.受教育程度对老年患者术后认知功能的影响[J].重庆医学,2010,39(23):3248-3249. 被引量：13
6胡蕊,王志峰,吕立召,王岚,王学义,王永良.高血压病对社区老年人认知功能的影响[J].临床荟萃,2013,28(9):1018-1020. 被引量：12
7Feng X, Degos V, Koch LG, et al. Surgery results in exaggerated and persistent cognitive decline in a rat model of the Metabolic Syndrome[J]. Anesthesiology, 2013,118 ( 5 ) :1098--1105.
8Murray C, Sanderson DJ, Barkus C, et al. Systemic inflammation induces acute working memory deficits in the primed brain: relevance for delirium[J]. Neurobiol Aging, 2012,33(3) :603--616.
9Dong Y, Wu X, Xu Z, et al. Anesthetic isoflurane increases phosphorylated tau levels mediated by caspase activation and Abeta generation[J].PLoS One,2012,7(6):e39386.
10Callaway JK, Jones NC, Royse AG, et al. Memory Impairment in Rats after Desflurane Anesthesia is Age and Dose Dependent[J]. J Alzheimers Dis, 2015,44 (3) : 995 -- 1005.

二级参考文献33

1冯锋,韩学青,陈建,尚兰,李娟.日常生活活动能力量表在痴呆筛查中的应用[J].临床精神医学杂志,2004,14(4):193-194. 被引量：65
2张作证.行为医学量表手册[M].北京:中华医学电子出版社,2005:177-179.
3Dijkstra JB,Olles J. Postoperative Cognitive Dysfunction. Versus complaints: a diserepancy in long-term findings [J]. Neuropsychol Rev, 2002,12(1) : 1.
4Dodds C, Allison J. Postoperative cognitive deficit in the elderly surgical patient[J]. Br J Anaesth, 1998,81 :449.
5Pratico C, Quattrone D, Lucanto T, et al. Drugs of anesthesia acting on central cholinergic system may cause postoperative cognitive dysfunction and delirium[J]. Med Hypothese, 2005,65 (5) : 972.
6Newman S, Stygall J, Hirani S, et al. Postoperative cognitive dysfunction after noneardiae surgery:a systematic re view[J]. Anesthesiology, 2007,106 (3) : 577.
7Fischer P, Jungwirth S, Zehemayer S, et al. Conversion from subtypes of mikl cognitive in payment to Alzheimer dementia[J]. Neurology, 2007,68(4):288.
8Yoshitani K, Kawaguchi M, Sugiyama N, et al. The association of high jugular bulb venous oxygen saturation with cognitive decline after hypothermic cardiopulmonary bypass[J]. Anesth Analg,2001,92:1370.
9Arehila A, Moreno S. Neuropsychological test performance in Auuaco Indians: an exploratory study[J]. J Int Neuropsyehol Soc, 2001,7: 510.
10张娜,黄文湧.高血压与认知功能关系的研究现状[J].中国老年学杂志,2007,27(19):1944-1947. 被引量：19