水凝胶防治化疗性静脉炎的临床研究

Clinical investigation of the effect of hydrogel on the prevention of phlebitis caused by chemotherapy

目的探索有效防治恶性肿瘤患者化疗性静脉炎的护理措施。方法将150例恶性肿瘤定期接受化疗的患者随机分为3组,水凝胶组、土豆片组和对照组,每组各50例。分别给予水凝胶外敷、新鲜土豆片外敷及常规预防措施,比较3组患者静脉炎的发生率、程度和发生时间。结果水凝胶组静脉炎发生率为8.0%,明显低于对照组(42.0%)和土豆片组(22.0%,P<0.05);水凝胶组静脉炎发生时间(6.2 d)明显长于对照组(3.6 d,P<0.05)。对照组和土豆片组静脉炎严重程度明显高于水凝胶组,3组之间比较,差异有统计学意义(P<0.05)。结论采用水凝胶外敷能有效防治恶性肿瘤患者化疗性静脉炎的发生。

Objective To investigate the effectiveness of hydrogel as a prevention measure of phlebitis caused by chemotherapy in carcinoma patients. Methods 150 patients in need of long-term chemotherapy were randomly divided into three groups with 50 subjects each： hydrogel group,potato chips group and control group. Incidence,degree and attacking time of phlebitis of each group were observed, recorded and compared. Results The incidence of phlebitis in hydrogel group was 8.0%,significantly lower than that of control group（42.0%） and potato chips group（22.0%）,both P 0.05. The attacking time of phlebitis in hydrogel group was 6.2 days,significantly longer than that of control group（3.6d）,P 0.05. The degree of phlebitis in control group and potato chips group were significantly heavier than that of hydrogel group,P 0.05. Conclusion Hydrogel could effectively prevent the occurrence of phlebitis caused by chemotherapy in carcinoma patients.