虹膜脉络膜在闭角型青光眼中的作用机制研究进展

The research progress of the iris choroid mechanism in angle-closure glaucoma

PACG是一种常见的不可逆的致盲性疾病。以往认为其特征性房角关闭的危险因素包括浅前房、短眼轴、厚晶状体等静态解剖因素，还包括虹膜动态变化，脉络膜膨胀等房角动态因素。随着各项眼科影像学技术的发展，人们能更细致地观察到眼球各解剖结构在房角关闭中的作用。其中，虹膜及脉络膜在闭角型青光眼中起到的作用已越来越为人们所重视，借助眼前节OCT（AS-OCT）等各种眼科影像学技术，我们对前房角关闭的机制有了新的认识，可进一步深入阐明虹膜脉络膜与房角关闭之间的联系，为闭角型青光眼早期诊断和个体化治疗做出指导。

Primary angle closure glaucoma （PACG） is a kind of common disease causing irreversible blindness. The traditional risk factors of the characteristic features of angle closure glaucoma include not only some static anatomical factors such as： shallower anterior chamber, shorter axial length and thicker lens, but also some dynamic factors including iris dynamic change, choroidal expansion. With the development of the technology of Ophthalmological iconography, more anatomical structures in the closure angle can be observed more carefully. Among them, the iris and choroid, which play important roles in PACG should be paid more attention. With the new techniques such as AS-OCT （anterior segment optical coherence tomographyanterior segment optical coherence tomography）, we can summarize some new comprehension of the mechanism of angle closure, in order to clarify the relation between iris, choroid and angle closure, thus to make better guidance for early diagnosis and personalized treatment of angle closure glaucoma.