摘要
本文结合肺部的解剖学和生理学特征以及肺结核的病理学特征重点阐释了抗结核药物肺部递送的优势和应关注的问题。通过近几年若干肺部递送抗结核药物的研究实例说明了肺结核治疗的这一新途径的可行性。
This review highlights the advantages of the pulmonary delivery of anti-TB agents and the associated concerns based on the understanding of the characteristics of both the anatomy and physiology of the lung and the TB pathology. The feasibility of this new drug delivery approach has been recently proven by some case-studies on the pulmonary delivery of anti-TB agents.
出处
《上海医药》
CAS
2016年第17期71-77,共7页
Shanghai Medical & Pharmaceutical Journal
关键词
肺结核
肺部递送
巨噬细胞靶向
空气动力学直径
tuberculosis
pulmonary delivery
macrophage targeting
aerodynamic diameter