早期应用前列地尔治疗急性脑梗死临床疗效观察

Observation of clinical effect by early application of alprostadil in the treatment of acute cerebral infarction

目的观察早期应用前列地尔治疗急性脑梗死的临床疗效。方法 80例急性脑梗死患者,随机分成对照组和实验组,各40例。对照组患者在常规对症治疗的基础上加用长春西汀治疗,实验组患者在常规对症治疗的基础上早期应用前列地尔治疗。对比两组疗效。结果实验组总有效率为97.5%,高于对照组的82.5%,差异具有统计学意义(P<0.05)。结论早期应用前列地尔治疗急性脑梗死临床疗效显著,安全可靠,具有临床推广和应用价值。

Objective To observe clinical effect by early application of alprostadil in the treatment of acute cerebral infarction. Methods A total of 80 acute cerebral infarction patients were randomly divided into control group and experimental group, with 40 cases in each group. The control group received additional vinpocetine to conventional symptomatic treatment, and the experimental group received additional alprostadil instead. Curative effects were compared between the two groups. Results The experimental group had higher total effective rate as 97.5% than 82.5% of the control group, and the difference had statistical significance（P〈0.05）. Conclusion Early application of alprostadil shows remarkably clinical effect in treating acute cerebral infarction. This method is safe and creditable, and it contains clinical promoting and applying value.