幽门螺旋杆菌与肝病的研究进展

Research progress in Helicobacter pylori and liver disease

幽门螺旋杆菌是一类寄生于消化道的微需氧菌,与慢性胃炎、胃溃疡等消化性疾病的发生关系密切。目前有研究表明在肝病的发生中也存在幽门螺旋杆菌感染,但两者之间的相关性及具体作用机制尚未阐明。本文通过复习相关文献,对幽门螺旋杆菌在病毒性肝炎、肝硬化、肝性脑病、肝癌、脂肪肝等肝脏疾病的发生和发展方面的研究进展进行综述。

Helicobacter pylori is a microaerophilic bacterium which parasitizes in the digestive tract and is closely related to the occurrence of various gastrointestinal diseases, such as chronic gastritis, gastric ulcers and so on. Recently, studies have shown that majority of patients with liver disease also suffer from Helicobacter pylori infection, but the correlation between them and the specific mechanism remain unclear. Through reviewing the related literatures, this review summarized the relationship between Helicobacter pylori and the development and progression of liver diseases, such as chronic hepatitis, fatty liver, liver cancer and hepatic eneephalopathy, etc.