视觉诱发电位诊疗系统治疗儿童弱视的效果观察

Effects of visual evoked potential diagnostic system on amblyopia in children

目的 探究视觉诱发电位诊疗系统在儿童弱视治疗中的临床效果和应用价值。方法 选取本院收治的100例进行空间频率弱视治疗训练的弱视患儿,均分为试验组与对照组。对所有患儿进行视力检测,待其瞳孔恢复正常、排除其他眼部疾病后,两组分别采用以下方式治疗：试验组使用视觉诱发电位诊疗系统（DV-100VEP）进行视觉诱发电位检测,找出最敏感空间频率作为刺激源,并以此频率为标准,制作弱视训练软件并刻录光盘,让患儿在家长的监督以及弱视训练软件指导下进行训练;对照组不需要通过视觉诱发电位找出最敏感频率,而是直接从低频率到高频率依次进行CAM训练仪、光栅、增视能弱视训练光盘进行训练。结果 治疗后随访6~12个月,试验组的有效率和治愈率均优于对照组（P〈0.05）。在试验组中,表现为开始治疗年龄越晚,疗效越差（P〈0.05）,其中3~6岁患儿治愈率和有效率最高,7~9岁患儿次之,10~12岁患儿最低;重度弱视组治愈率和有效率最低,中度弱视组次之,轻度弱视组最高（P〈0.05）。结论 通过不同空间频率视觉诱发电位检测,找出敏感的个体化空间频率,为患者提供针对性训练,治疗效果显著,且年龄越小、弱视程度较轻者效果更为明显,值得临床推广应用。

Objective To explore the clinical effect and application value of visual evoked potential diagnostic system on amblyopia in children. Methods A total of 100 children with amblyopia admitted to our hospital for spatial frequency amblyopia treatment training were selected and divided into an experiment group and a control group （n=50, respectively）. All children patients underwent vision test. When their pupils return to normal and other eye diseases are excluded, the two groups were treated as follows： Visual evoked potential detection was conducted on the experiment group with visual evoked potential diagnostic system（DV-100VEP） to find out the most sensitive spatial frequency as stimulus and produce amblyopia training software, and burn a CD on the basis of such frequency for training of children patients under the guidance of parents and amblyopia training software; it is unnecessary to find the most sensitive frequency through visual evoked potential for the control group, but directly carry out the training through CAM training instrument, grating diaphragm, and vision improvement amblyopia training CD from low frequency to high frequency. Results According to the 6-12-month follow-up visit after the treatment, the effective rate and cure rate of the experiment group were higher than those of the control group （P 〈 0.05）. In the experiment group, it showed that the elder the age, the poorer the efficacy （P 〈 0.05）： three to six-year old children had the highest cure rate and effective rate, followed by those of seven to nine-year old children, and then 10-12-year old children; the cure rate and effective rate in the severe amblyopia group were the lowest, followed by those in the moderate amblyopia group, then the mild amblyopia group （P 〈 0.05）. Conclusion To find out the sensitive Individual spatial frequency through visual evoked potential detection at different spatial frequencies to provide patients with targeted training has obvious effect. The younger the children are, the better the effect will be. This treatment is worth clinical popularization and application.