老年脂肪肝患者血常规及部分生化指标结果分析

Analysis on results of blood routine and partial biochemical indexes in elderly patients with fatty liver

目的探讨老年脂肪肝患者血常规及部分生化指标的临床意义。方法选取2015年10月到该院体检的530例老年人,分为脂肪肝组(166例)和非脂肪肝组(364例),对其血常规、血脂、肝功能指标进行检测和分析。结果与非脂肪肝组相比,脂肪肝组的白细胞计数(WBC)、嗜酸性细胞比例、血红蛋白浓度(Hb)、红细胞计数(RBC)、红细胞比容(HCT)、平均红细胞血红蛋白含量(MCH)、平均红细胞血红蛋白浓度(MCHC)、红细胞分布宽度(RDW)、血小板分布宽度(PDW)差异均有统计学意义(P<0.01);淋巴细胞比例、单核细胞比例、红细胞平均体积(MCV)、平均血小板体积(MPV)明显增加(P<0.05),血小板计数(PLT)减少(P<0.05),而其余指标比较差异无统计学意义(P>0.05);脂肪肝组的三酰甘油(TG)、胆固醇(TC)、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)水平与非脂肪肝组相比,差异均有统计学意义(P<0.05)。结论老年脂肪肝患者存在血液指标的改变,定期检测血常规、血脂、肝功能有助于脂肪肝患者的早期诊断和治疗。

Objective To study the clinical significance of blood routine and partial biochemical indexes in elderly patients with fatty liver.Methods Totally 530 elderly people undergoing the physical examination in our hospital during October 2015 were selected and divided into the fatty liver group（166cases）and non-fatty liver group（364 cases）.The blood routine,blood lipid and liver function were detected and analyzed.Results WBC count,eosinophil proportion（EO%）,hemoglobin（Hb）concentration,RBC count,hematocrit（HCT）,mean corpuscular hemoglobin（MCH）,mean corpuscular hemoglobin concentration（MCHC）,RBC distribution width（RDW）and platelet distribution width（PDW）had statistically differences between the fatty liver group and the nonfatty liver group（P〈0.01）;the lymphocyte proportion,monocytes proportion,mean corpuscular volume（MCV）and mean platelet volume（MPV）in the fatty liver group were significantly increased（P〈0.05）and platelet（PLT）count was significantly decreased（P〈0.05）,and the differences of other indexes had no statistical significance（P〉0.05）;the levels of triglyceride（TG）,cholesterol（TC）,alanine aminotransferase（ALT）and aspartate aminotransferase（AST）had statistical difference between the fatty liver group and the non-fatty liver group（P〈0.05）.Conclusion The changes of blood indexes exist in the elderly patients with fatty liver.The regular detection of blood routine,blood lipid and liver function can be conducive to early diagnosis and treatment in the patients with fatty liver.