颅盖骨朗格汉斯组织细胞增生症的CT和MRI表现

CT and MRI findings of Langerhans cell histocytosis in cranial bone

目的:探讨颅盖骨朗格汉斯组织细胞增生症的CT及MRI特征。方法;回顾性分析12例经病理证实的颅盖骨朗格汉斯组织细胞增生症的CT及MRI表现。结果:主要CT表现为肿瘤起源于颅骨板障并侵犯颅骨内外板,可见边界清楚的"梯形"骨质破坏区,病灶呈"葫芦状"软组织密度影,6例密度不均匀,其中3例残留小骨片、1例残留脂质。MR T1WI上肿瘤呈低-等信号,T2WI上呈混杂高信号,DWI上5例呈高信号、1例呈略低信号,增强扫描呈中度强化。7例病变侵犯硬脑膜。结论:颅盖骨朗格汉斯组织细胞增生症的影像学表现有一定特征性,综合运用CT与MRI检查能提高术前诊断准确性。

Objective：To explore the CT and MRI features of Langerhans cell histocytosis in cranial bone. Methods： CT and MRI manifestations of 12 cases with Langerhans cell histocytosis in cranial bone proven pathologically were retro- spectively analyzed. Results：On CT,the lesions mainly had two features：well defined ＂trapezoid＂ osteolytic destructions in the diplo o{ skull with inner an6 outer plate involved;＂ gourd-shape＂ soft tissue mass, uneven density was found in 6 lesions with residual bones in 3 cases and fat in 1 case. On MRI,all lesions showed hypo- to iso-intensity on TlWI and heteroge- neous hyperintensity on T2 WI,hyperintensity in 5 cases and slight hypointensity in 1 case on DWI,and moderate enhance- ment on Gadolinium-enhanced MR images. Involvement of dura mater was found in 7 cases. Conclusion： Calvarial bone Langerhans cell histocytosis has certain imaging characteristics,combination of CT and MRI can further improve the preo- perative diagnostic accuracy.