冠心病生存质量与中医证候轻重的相关性分析

Study of Pertinence on Quality of Life and Different Severity of TCM Syndromes for Patients with Coronary Heart Disease

目的研究分析冠心病患者的生存质量与中医证候轻重的相关性。方法应用已构建的冠心病中医证候疗效综合评价体系作为评价工具,冠心病患者入院后3d内与出院前3d填写生活质量表(SF-36)与中医证候临床观察表。以入出院生存质量差值与入出院证候轻重各指标差值进行比较。结果生存质量评分与证候综合疗效评价体系的各个层面均存在相关关系。在11个基本证候层面中,水湿证、气滞证、实热证与生存质量有显著的相关性;在实证与虚证层面,虚证与生存质量评分的相关性较为显著;在生存质量与证候总分之间,有显著的负相关关系(相关系数-0.939)。结论在冠心病中医综合疗效评价指标体系中,中医证候在各个层面与生存质量存在相关关系,且与证候总评价有较强相关性。

Objective To study the pertinence on quality of life and severity degree of TCM syndromes for patients with coronary heart disease （CHD）. Methods Apply coronary heart disease （CHD） TCM efficacy evaluation system as an evaluation tool. Patients who met the inclusion criteria fill out the quality of life table （SF-36） and the clinical observation of TCM syndrome table, within 3 days admission and 3 days before discharge. To Comparison the difference of quality of life and syndrome severity each index between the admission and discharge. Results The total score of TCM syndromes has the correlation with quality of life （SF- 36）, and it could reflect the progress of CHD and quality of life in patients. Dampness syndrome, qi stagnation syndrome and excess-heat syndrome are significantly correlated with the quality of life in the 11 basic syndromes. The deficient syndromes is more significantly correlated with the quality of life compared with that of excessive syndromes study in this level. There is the significant negative correlation between the quality of life and the total score of syndrome （correlation coefficient-0. 939）. Conclusions There is the significant correlation between the quality of life and the all levels of the coronary heart disease （CHD） TCM efficacy evaluation system, and the correlation of the TCM syndrome total score and the quality of life is relatively strong. As well as the quality of life, the TCM syndrome total score is also a comprehensive evaluation index of the coronary heart disease.