组织多普勒成像技术对系统性红斑狼疮心脏功能评价的研究进展

Value and research progress of tissue Doppler imaging in evaluating cardiac function of patients with systemic lupus erythematosus

目的探讨组织多普勒成像技术（TDI）对系统性红斑狼疮心脏功能的评价及其进展。方法通过pubmed数据库、中国知网数据库查阅2009年1月2015年2月国内外关于组织多普勒成像技术在系统性红斑狼疮心脏病变中的应用有关文献，进行总结归类。结果发现系统性红斑狼疮心脏病变表现是多方面的，包括心肌、心包、瓣膜以及冠脉等不同程度的损害。这些损害2D超声早期难以判断；而运用TDI相关指标Sm、e’／a’值、et值、E／e’比值不仅可以对其进行早期评估，还可以对其严重程度及预后可做出准确的判断，从而为临床及时处置提供决策信息。结论TDI不但能够早期并较好的评价系统性红斑狼疮心脏功能改变，而且对心脏损害的系列病变的检测也具有重要价值。

Objective To explore the value and research progress of the Tissue Doppler Imaging in evaluating cardiac function of patients with systemic lupus erythematosus. Methods To review and summarize the relevant literatures in PubMed database and CNKI database from January 2009 to February 2015 concerning the application of Tissue Doppler Imaging in cardiac involvement of systemic lupus erythematosus. Results Find varieties of heart disease complicated with systemic lupus erythematosus, including varying degrees of impairment about myocardial, pericardium, coronary artery and valvular, because of the damage is difficult to determine by two-dimensional ultrasound early, using TDI index such as Sm, e＇/a＇ value, e＇ value and E/e＇ ratio can not only early assessment, but also can make accurate judgment and about the damage degree and the prognosis, so as to provide decision-making information for clinical treatment timely. Conclusions Tissue Doppler Imaging has not only high sensitivity for early change of cardiac function complicated with systemic lupus erythematosus, but also higher value for detecting the series heart diseases about systemic lupus erythematosus.