终末期肝病营养代谢及营养支持

Nutrition metabolism and nutrition support in end-stage liver disease

肝脏在营养调控中起到核心作用，终末期肝病患者常由于代谢异常出现营养不良，营养不良与终末期肝病患者的预后息息相关，因此正确的营养评估和支持显得尤为重要。单纯饮食摄入并不能满足终末期肝病患者的营养需求，近些年，肠内外营养制剂的使用已经大大改善了患者的营养状况，但仍缺乏一个“金标准”。如何制订适宜的营养支持方案是临床医师亟需解决的问题，本文就终末期肝病患者的营养相关问题加以阐述，旨在为终末期肝病患者个体化的营养干预提供借鉴。

Liver plays a central role in regulation of nutrition. Due to metabolic abnormalities, patients with end-stage liver disease often demonstrate undernutrition, which has a close relationship with the prognosis of the patients. Correct nutritional assessment and nutrition support is therefore very important. Dietary intake alone could not meet the nutritional needs of patients with end-stage liver disease. In recent years, the use of enteral and parenteral nutrition formulation has significantly improved the nutritional status of such patients, but there still lacks a ＂gold standard. ＂ How to develop appropriate nutrition support regimens is a challenge for cli- nicians. This paper summarizes nutrition-related issues in patients with end-stage liver disease, aiming to provide a reference for individualized nutritional intervention for patients with end-stage liver disease.