2015年医院妇产科围手术期抗菌药物应用分析

Analysis of Antibiotics Used during Perioperative Period in the Department of Obstetrics and Gynecology in 2015

目的分析医院妇产科围手术期抗菌药物的应用情况，优化抗菌药物的使用。方法对2015年医院妇产科150例手术患者抗菌药物的应用情况进行统计分析。结果抗菌药物使用率排在前3的分别为注射用头孢呋辛钠（74例，49．33％）、注射用头孢他啶（47例，31．33％）、甲硝唑（15例，10．00％）。用药持续时间≤24h的25例（16．67％），24h〈用药持续时间≤48h的81例（54．00％）．3～7d的37例（24．67％）。预防用药时机，术前2～48h的有12例（8．00％），术前0．5～2h或麻醉开始时121例（80．67％），术后17例（11．33％）。结论该院抗菌药物在妇产科围手术期使用情况基本合理，但也存在用药时间偏长、给药时机不恰当的现象，需要进一步完善合理用药管理。

Objective To analyze the usage of antibiotics during perioperative period in the Department of Obstetrics and Gynecology in the hospital, and to optimize the use of antibiotics. Methods Statistical analysis was performed on 150 cases of gynecological and obstetric operation in August 2015. Results The top 3 usage of antibacterial drugs were cefuroxime sodium injection in 74 cases, accounting for 49.33% ; ceftazidime injection in 47 cases, accounting for 3l. 33% ; metronidazole in 15 cases, accounting for 10. 00%. 25 cases of medication duration were less than or equal to 24 h （16.67%）; 81 cases 24 h 〈 T≤48h （54.00%）; 37 cases of 3-7 d （24.67%）.Preoperative 2-48 h of the prevention of medication was 12 cases, accounting for 8.00%;preoperative 0.5-2 h or anes- thesia at the beginning was 121 cases, accounting for 80. 67%; postoperative 17 cases, accounting for 11.33%. Conclusions The peri-operative use of antibiotic drugs in the Department of Obstetrics and Gynecology in the hospital is basically reasonable, but there are still problems such as medication time too long, inappropriate timing of administration, etc.,which require further improvement on the management for rational drug use.