摘要
目的:在广东省内对各精神专科医院进行氯氮平治疗药物监测(TDM)室间质量评价。方法:通过发放调查问卷的形式了解广东省内精神专科医院氯氮平治疗药物监测所使用高效液相色谱仪的相关参数,并通过发放统一质控品对省内各专科医院进行氯氮平治疗药物监测室间质量评价。结果:省内6家精神专科医院氯氮平TDM低、中、高浓度质控品的检测合格率分别为66.67%,66.67%,83.33%。结论:在省内开展氯氮平治疗药物监测室间质评是十分必要的。
Objective： To implement the external quality assessment （EQA） of clozapine for therapeutic drug monitoring （TDM） among psychiatric hospitals in Guangdong. Methods： The parameters of HPLC used by the hospitals were understood through questionnaires. The EQA of clozapine for TDM was implemented by distributing the quality control serum. Results： The qualified rate of clozapine in the quality control serum at low, medium and high concentrations for TDM was 66.67%, 66.67% and 83.33%, respectively. Conclusion： It is necessary to implement EQA of clozapine for TDM in Guangdong.
出处
《中国药师》
CAS
2016年第9期1791-1793,共3页
China Pharmacist
基金
中山市科技计划项目(编号:2014A1FC148)
关键词
氯氮平
治疗药物监测
质量控制
室间质评
Clozapine
Therapeutic drug monitoring
Quality control
External quality assessment
