慢性萎缩性胃炎危险因素病例对照研究

A case-control study on risk factors of chronic atrophic gastritis

目的探讨慢性萎缩性胃炎危险因素,为疾病防治提供科学依据。方法以1∶1配对病例对照研究方法,对148例慢性萎缩性胃炎病例和148例健康对照者进行问卷调查。用卡方检验、单因素和多因素条件logistic回归法进行分析。结果烧烤(OR=7.00)、吸烟(OR=3.18)、口味偏咸(OR=2.38)、家族慢性胃病史(OR=2.22)和饮酒(OR=2.14)是慢性萎缩性胃炎的危险因素,而经常吃水果(OR=0.33)、新鲜蔬菜(OR=0.35)、奶制品(OR=0.42)和个性温和(OR=0.49)是保护因素。结论家族慢性胃病史、饮食生活习惯及精神心理因素等对慢性萎缩性胃炎发病有影响。

Objective To study the risk factors of chronic atrophic gastritis for the disease control and prevention. Methods Totally 148 chronic atrophic gastritis cases and 148 control subjects were investigated with questionnaire and the data were analyzed by Chi-square test and conditional logistic regression model. Results Burnt foods （OR = 7. 00）,smoking （OR =3.18）,high salt foods （OR =2.38）,family history of chronic gastropathy （OR =2.22） and alcohol drinking （OR =2.14） were risk factors of chronic atrophic gastritis, and fruits （OR = 0.33）, fresh vegetables fORgO. 35）,milk products （OR=0.42） and gentle personality feature （OR =0.49） were protective factors. Conclusions Family history of chronic gastropathy,diet and lifestyle,and psychological factors may be the effective factors on pathogenesis of chronic atrophic gastritis.