目标性体温管理在脓毒症患者临床应用价值的研究进展

Advances in targeted temperature management in sepsis and the clinical value of application in patients

脓毒症是ICU患者的常见症之一，可以导致较高的病死率。一些动物实验及临床研究显示目标性体温管理对脓毒症各脏器功能具有保护作用，但是在脓毒症中体温管理的最佳时机、持续时间、干预措施、目标温度等仍存在较大争议，脓毒症患者能否从体温管理的临床上获益仍值得进一步研究，本文就近期脓毒症体温管理的研究进展作一综述。

Sepsis is one of the serious illnesses leading to high mortality in ICU. Some animal experiments and clinical trails show that target temperature management has a protective effect on target organ function in sepsis, but the optimal timing, length of targeted temperature managment continued, intervention measures, and optimal target temperature obtained in sepsis remains in the great controversy. Whether the patients with sepsis would be truly benefited from the body temperature management is still worthy issue for further study. The aim of this article reviews is to trace the recent research progress on the body temperature management in sepsis.