早期肠内营养联合微生态制剂对危重病患者胃肠功能恢复的影响

Effects of early enteral nutrition combined with bifid-triple viable on recovery of gastrointestinal function in critically ill patients

目的观察早期肠内营养联合微生态制剂在改善危重病患者胃肠功能的临床疗效。方法 ICU危重病患者276例随机均分成两组:试验组患者行早期肠内营养联合双歧杆菌三联活菌鼻饲治疗;对照组患者单纯行早期肠内营养治疗。比较两组治疗前后相关实验室检测指标,分析胃肠道并发症发生情况。结果两组患者治疗10d后,白蛋白(Alb)升高,Hb、C反应蛋白(CRP)、乳酸脱氢酶(LDH)和WBC计数降低(P<0.05),试验组的改善程度优于对照组(P<0.05)。试验组患者腹胀、腹泻、呕吐、便秘和上消化道出血发生率也低于对照组(P<0.05)。结论危重病患者早期肠内营养联合微生态制剂治疗能有效保护胃肠道功能,维护机体内环境稳定,减少并发症。

Objective To observe the effects of early enteral nutrition combined with bifidtriple viable（a microecological preparation）on the recovery of gastrointestinal function in critically ill patients.Methods A total of 276 patients was eqally assigned into two groups of A（treated with early enteral nutrition combined with bifid-triple viable nasal feeding for 10days）and B（treated with early enteral nutrition alone as the control）.The gastrointestinal function and complications were observed,albumin（Alb）,Hb,C-reactive protein（CRP）,lactate dehydrogenase（LDH）and WBC were detected.Results Compared to before,Alb was increased,and Hb,CRP,LDH and WBC were decreased after treatment for 10days（P〈0.05）,the changes of which were more in group A than those in group B（P〈0.05）.The incidence rates of bloating,constipation,diarrhea,vomiting and upper digestive tract hemorrhage were lower in group A than those in group B（P〈0.05）.Conclusion The early enteral nutrition combined with bifid-triple viable is effective in protecting gastrointestinal function,maintaining stable homeostasis,and reducing complications in critically ill patients.