摘要
Hedgehog信号通路在动物胚胎期及出生后骨骼肌的生长发育过程中发挥着重要作用。本文综述了Hedgehog信号通路对骨骼肌细胞增殖分化及肌纤维特性的调控作用及其在骨骼肌发育过程中与其它信号通路交互作用最新研究进展,为畜禽肉品质改良和肌肉相关疾病治疗提供理论基础。
Hedgehog signaling pathway plays an important role in embryonic and postnatal growth and development of skeletal muscle. This article reviewed the latest research progress on the role of the Hedgehog signaling pathway in myocyte proliferation and differentiation,and its interaction with other signaling pathways in skeletal muscle development. It will provide the fundamental basis for the improvement of livestock and poultry meat quality and the therapy of skeletal muscle disease.
出处
《中国生物化学与分子生物学报》
CAS
CSCD
北大核心
2016年第9期994-997,共4页
Chinese Journal of Biochemistry and Molecular Biology
基金
国家重点基础研究发展计划(973计划
No.2015CB943102)资助~~
关键词
HEDGEHOG信号通路
骨骼肌
增殖分化
肌纤维特性
Hedgehog signaling pathway
skeletal muscle
proliferation and differentiation
muscle fiber speciality
