CEA联合CA19—9检测对Ⅳ期胃癌腹膜转移的诊断研究

目的探讨血清CEA和CA19—9联合检测在Ⅳ期胃癌腹膜转移患者的诊断、鉴别中的作用。方法采用酶偶联吸附法和化学发光免疫分析法对胃癌腹膜转移患者、无腹膜转移胃癌患者和正常人群进行血清CEA、CA19—9检测，分析两者联合检测在诊断和鉴别Ⅳ期胃癌腹膜转移中的作用。结果转移组血清CEA和CA19—9水平均显著高于其他两组（P〈0．05）；无转移胃癌组CEA和CA19-9水平明显高于对照组（P〈0．05）。结论CEA和CA19—9水平在诊断Ⅳ期胃癌腹膜转移中有着重要作用，二者联合检测可以作为该病临床诊断方法，且操作简单，值得临床推广。

Objective To investigate the serum CEA and CA19-9 joint detection in IV peritoneal metastasis in patients with gastric cancer diagnosis, identify the role of Methods using enzyme coupling adsorption and chemical luminescence immunoassay, peritoneal metastasis in patients with gastric cancer peritoneal metastasis patients with gastric cancer and normal detection of serum CEA and CA19-9, analyzed two joint detection in the diagnosis and differential phase Ⅳ peritoneal metastasis of gastric cancer, Results transfer group serum CEA and CA19-9 levels were significantly higher than the other two groups （P〈0.05）; No transfer of CEA and CA19-9 gastric cancer group was obviously higher than that of control group （P 〈 0.05）. Conclusion in the diagnosis of CEA and CA19-9 IV pexltoneal metastasis plays an important role in gastric cancer, the joint detection method can be used as a clinical diagnosis of the disease, anti the opetation is sidle, worth clinical promotiota.