低剂量泼尼松在儿童过敏性紫癜临床效果情况分析研究

目的研究分析低剂量泼尼松在治疗儿童过敏性紫癜的临床疗效。方法：褪取62例过敏性紫癜患儿，随机分为对照组和观察组各31例，其中对照组采用常规剂量泼尼松治疗，观察组采用低剂善泼尼松治疗。结果：观察组的各种症状消退时间与对照组相比，差异无统计学意义（P〉0．05），紫癜复发率和不良反应发生率观察者均明显低于对照组（P〈0．05）。结论：低剂量泼尼松在治疗儿童过敏性紫癜方面具有明显的临床疗效，且具有高度的安全性和有效性，对减轻肾脏损害和防止复发有较好的疗效，在临床牛值得应用和推广。

Objective To study the clinical effect of low dose of prednisene in the treatment of children allergic purpura. Methods： A total of December 2014 and 2015 December in our hospital admitted to the pediatric department of 62 cases of allergic purpura in children as the research object, all the children were randomly divided into the observation group and the control group, 31 cases in each. The control group was treated with routine dose of prednisone in the treatment of, the observation group with low dosage of prednisone therapy.Results：Observation greop with a variety of symptoms subsided and the control group compared with no obvious abnormalities （P〉0.05）, purpura recurrence rate and adverse reaction occurred rate observer were significantly lower than that of the control group （P〈0.05）. Conclusion：Low dose prednisone has obvious clinical curative effect in treating children allergic purpura and has high safety and effectiveness, to alleviate the damage of kidney and prevent recurrence have better curative effect, and is worthy of application and promotion in clinical.