儿童急性呼吸道病毒感染病原学分析

目的探讨深圳地区小儿呼吸道病毒感染的病原学分布情况。方法：采用PCR法检测呼吸道感染患儿急性期鼻咽部分泌物中hMPV、hCoVNL63和HKU1、hBoV含量，并同时检测RSV、ADV、IV、PIV含量。结果：所检测的919病例中，hMPV、heoVNL63、heoVHKU1及hBoV阳性率分别为4．46％、L85％、0．54％及2．72％，RSV、ADV、IV及PIV阳性率分别为8．59％、14．25％、9．36％及1．41％，感染存在季节和年龄差异。结论：除外常见病毒，近年新发现的呼吸道病毒hMPV、hCoVNL63、hCoVHKU1及hBoV在我院儿童急性呼吸道感染的病毒性病原学中占有一定比例，应引起临床工作者得重视。

Objective To investigate the Pathogenic Distribution of respiratory virus infection in children in Shenzhen area. Methods：PCR method was used to detect the contents of hMPV,hCoV NL63 and HKU1 ,hBoV in the patients with acute respiratory tract infection, and the contents of IV, RSV, ADV, PIV were detected. Results：In the 919 cases, the positive rates of hMPV, hCoV NL63, hCoV HKU1 and hBoV were 4.46%, 1.85%,0.54% and 2.72% he positive rate of NL63 hCoV was 1.85%,respectively.The positive rates of RSV, ADV, IV and PIV were 8.59%, 14.25%, 9.36% and 1.41%ce, respectively. There was difference between different seasons and age groups. Conclusion：Except for common viruses, hMPV, hCoV-NL63, hCoV-HKU1 and hBoV in children with acute respiratory tract infection in Shenzhen City, Share a certain proportion, it should pay more attention to the clinical workers.