ERCP术后胰腺炎的危险因素与鼻胆管引流预防的作用

目的浅析内镜逆行胰胆管造影术术后发生胰腺炎危险因素及鼻胆管引流对预防胰腺炎的作用。方法：行ERCP术治疗60例，分作研究组与对照组各30例，研究组术后置入鼻胆管引流，对照组未置入鼻胆管引流，分析胰腺炎ERCP术后的危险因素，比较两组患者治疗效果。结果：研究组患者术后发生胰腺炎的概率为6．67％，明显低于对照组的23．33％，且研究组术后3、12、24 h血淀粉酶水平显著低于对照组，血清淀粉酶水平恢复正常时间、症状缓解时间、住院时间等均短于对照组（P〈0．05），对比有统计学意义。结论：女性，插管次数≥3次是患者ERCP术后发生胰腺炎的危险因素，而鼻胆管引流可有效预防ERCP术后胰腺炎的发生，是ERCP术后发生胰腺炎的保护因素。

Objective： To analyze the risk factors of pancreatitis and the effect of Methods： Receive the parallel ERCP treatment of patients from our hospital in May biliary drainage on the prevention of pancreatitis alter endoscopic retrograde. 2014 - 2015 years 5 months, 60 patients were randomly selected, as the study group and the control group, and each group has 30 patients with study group 30 cases of patients with postoperative placed nasobiliary drainage, the control group of 30 cases of patients with postoperative not placed nasobiliary drainage, analysis of the risk factors for post ERCP pancreatitis, compared two groups of patients with therapeutic effect. Results： Patients in study group occurrence probability of pancreatitis was 6.67%, significantly lower than the control group of 23.33% and in group after 3h, 12h, 24h blood amylase level was significantly lower than that of the control group research, serum amylase level recovery normal time, remission time, hospitalization time were shorter than that of the control group （P 〈 0.05）, compared with statistical significance. Conclusion： Female, intubation times greater than or equal to three times is risk factors of pancreatitis after ERCP patients, and nasal biliary drainage can prevent post ERCP pancreatitis after the occurrence of, is the protective factors of pancreatitis after ERCP.