浅析氯吡格雷及前列地尔在急性脑梗死治疗中的应用

目的浅析氯吡格雷及前列地尔在急性脑梗死治疗中的应用效果。方法：选择急性脑梗死患者120例，随机分为参照组和治疗组各60例，所有患者均实施内科综合治疗，给予参照组采用氯吡格雷实施治疗，治疗组采用氯吡格雷联合前列地尔实施治疗。结果：治疗后，治疗组的IL-6、TNF—a和CRP等生化指标改善程度均明显好于参照组；治疗组的NIHSS评分（1l 97±1．1）分明显低于参照组（4．83±1．5）分；参照组的治疗总有效率为75％，治疗组为96．7％，治疗组的治疗总有效率明显比参照组高。上述各指标差异显著（P〈0．05）。结论：采用氯吡格雷及前列地尔治疗急性脑梗死可以取得非常显著的治疗效果，能够有效的降低各项生化指标水平，改善了患者的神经功能，具有非常显著的安全性，值得临床进一步推广使用。

Objective： To analyze the clopidogrel and lead in application effect in the treatment of acute cerebral infarction. Methods：120 eases of patients with a- cute cerebral infarction, according to the random indicator method were randomly divided into control group and treatment group, 60 patients with groups, all patients were implementing internal medicine comprehensive treatment, gives the reference group with clopidogrel treatment, treatment group of patients with elopidogrel. Results： After different treatment methods, treatment group of IL - 6, TNF alpha and CRP improved biochemical indicators were significantly better than control group; Treatment group of NIHSS score （1.97-1.1） significantly lower than the control group （4.83-1.5）, treatment group of nerve function to improve the situation bet-ter than control group; The treatment of control group total effective rate was 75%, total effective rate of treatment group was 96.7%, total effective rate of treatment group was obviously higher than control group. Significant difference was found in two sets of＇the above indicators, a comprehensive comparison, has obvious statisti- cal significance （P〈0.05）. Conclusion： The adoption of clopidogrel and front row, the treatment of acute cerebral infarction can obtain significant treatment effect, can effectively reduce the biochemical indicators level, improve the patient＇s nerve function, has a very significant security, is worth further clinical use.