阿司匹林肠溶片联合氯吡格雷治疗冠心病心绞痛的临床应用研究

目的探讨冠心病心绞痛患者接受阿司匹林肠溶片和氯吡格雷联合治疗的临床疗效。方法：选择冠心病心绞痛患者110例，将其随机均分为2组，对照组采用阿司匹林肠溶片治疗，观察组应用阿司匹林肠溶片和氯吡格雷联合治疗，对比2组患者治疗后的临床疗效。结果：观察组患者治疗的总有效率为90．996，远高于对照组的74．5％；观察组患者的心绞痛发作次数和持续时间均少于对照组，而心绞痛发作间隔时间长于对照组，2组对比存在显著性差异母〈0．05）。结论：阿司匹林肠溶片和氯吡格雷联合应用治疗冠心病心绞痛取得了良好的临床疗效，患者的临床症状明显改善，不良反应较为轻微，值得大力推广。

Objective To study the patients with coronary heart disease angina pectoris treated with clopidogrel and aspirin enteric-coatedmetformin hydrochloride combined clinical curative effect. Methods： January 2013 - December 2015 in our hospital for treatment of 110 cases ofpatients with coronary heart disease angina as the research object, which are divided into two groups at random, the control group treated with aspirinenteric-coated mefformin hydrochloride, the observation group used aspirin enteric-coated mefformin hydrochloride and combination treatment withclopidogre], comparing the clinical curative effect of two groups of patients after treatment. Results： The observation group of patients treatment thetotal effective rate was 90.9%, far higher than the control group 74.5%; Observation group of patients with angina frequency and duration are far lessthan the control group, and angina time interval is far longer than the control group, two groups of contrast exists significant difference （P〈0.05）.Conclusion： Clopidogrel and aspirin enteric-coated mefformin hydrochloride joint used in the treatment of coronary heart disease angina pectorisachieved good clinical effect, the patient＇s clinical symptoms improved significantly, adverse reactions are mild, is worth promoting.