摘要
微小RNA(miRNA)是一种新型的非编码RNA,能在转录后水平调控基因的表达,且参与人体多种生理和病理过程的调控。近年来,研究表明,miRNA异常表达在糖尿病及其并发症的发生发展中起重要作用。本文就miRNA与糖尿病及其并发症的关系作简要综述。
As a new type of non-coding RNA, microRNA could regulate gene expression at the post-transcriptional level, and participate in the regulation of various human physiological and pathological processes. Recent studies indicated that the abnormal expression of miRNA played an important role in the occurrence and development of diabetes and its complications. Here, we reviewed the relationship between miRNA and diabetes and its complications.
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2016年第9期845-848,共4页
Chinese Journal of Diabetes
基金
教育部留学归国基金[教外司留(2014)1685号]
湖南省科技厅资助项目(2015JC3085)
南华大学留学归国基金1项(2013XQD49)
南华大学研究生科研创新项目(2015XCX36)
关键词
微小RNA
糖尿病
糖尿病并发症
microRNA（miRNA）
Diabetes mellitus
Diabetic complication
