双重打击淋巴瘤的临床特征和治疗探讨

Re exploration of double-hit lymphomas

目的探讨双重打击淋巴瘤的病理表现、治疗方法和治疗效果。方法 2013年1月-2015年10月接受治疗的双重打击淋巴瘤的患者3例,患者采用DA-EPOCH-R化疗模式。结果随访后显示患者胸部CT检查中肝脏右叶的低密度病灶明显减小,胃肠道部位异常密度阴影明显降低,腹膜淋巴结肿大症状明显减轻,患者恢复良好。结论双重打击淋巴瘤患者的病变症状较为明显,采用DA-EPOCH-R治疗的方式能够有效治疗。

Objective To investigate the lymphoma pathology, treatment methods and treatment effect of double-hit lymphomas. Methods From January 2013 to October 2015 in our hospital, three cases of double-hit lymphomas patients were received as the objects, and detected the patients＇ blood,blood biochemistry, urine, tumor markers, chest CT, gastroscopy and examination of bone marrow tissue immunity. All the patients, were treated with DAEPOCH-R therapy. Results The follow-up chest CT examination showed that patients＇ low-density lesions of the right lobe of the liver was significantly reduced, gastrointestinal site abnormal density shadow significantly reduce, retroperitoneal lymph nodes reduced significantly. The patients recovered well. Conclusion The symptoms of double-hit lymphomas are more obvious, and DA-EPOCH-R therapy is an effective mannerin the treatment.