期刊文献+

盐酸曲美他嗪治疗冠心病不稳定型心绞痛的临床评估 被引量:4

Clinical evaluation of trimetazidine hydrochloride in the treatment of coronary heart disease unstable angina pectoris
下载PDF
导出
摘要 目的:探讨盐酸曲美他嗪治疗冠心病不稳定型心绞痛的临床疗效。方法:收治不稳定型心绞痛患者85例,随机分为对照组和观察组,对照组采用常规治疗,观察组在对照组基础上加用盐酸曲美他嗪,比较两组治疗效果。结果:观察组的治疗效果明显优于对照组(P<0.05)。结论:盐酸曲美他嗪治疗冠心病不稳定型心绞痛的临床疗效显著。 Objective:To explore the clinical effect of trimetazidine hydrochloride in the treatment of coronary heart disease unstable angina pectoris.Methods:85 patients with unstable angina pectoris were selected.They were randomly divided into the control group and the observation group.The control group was given conventional treatment.The observation group added trimetazidine hydrochloride on the basis of the control group.We compared the treatment effect of two groups.Results:The treatment effect of the observation group was significantly better than the control group(P〈0.05).Conclusion:The clinical effect of trimetazidine hydrochloride in the treatment of coronary heart disease unstable angina pectoris was significant.
出处 《中国社区医师》 2016年第27期29-29,31,共2页 Chinese Community Doctors
关键词 不稳定型心绞痛 盐酸曲美他嗪 疗效 Unstable angina pectoris Trimetazidine hydrochloride Clinical effect
  • 相关文献

参考文献4

二级参考文献37

  • 1田志,陈明.曲美他嗪的临床应用[J].第三军医大学学报,2005,27(7):685-687. 被引量:12
  • 2李小鹰.阿司匹林在动脉硬化性心血管疾病中的临床应用:中国专家共识(2005)[J].中华心血管病杂志,2006,34(3):281-284. 被引量:193
  • 3无.慢性稳定性心绞痛诊断与治疗指南[J].中华心血管病杂志,2007,35(3):195-206. 被引量:2053
  • 4Kantor PF,Lucien A,Kozak R,et al.The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase[J].Circ Res,2000,86(5):580-588.
  • 5Allibardi S,Chierchia SL,Margonato V,et al.Effects of trimetazidine on metabolic and functional recovery of postischemic rat hearts[J].Cardiovasc Drugs Ther,1998,12(6):543-549.
  • 6Belardinelli R,Purcaro A.Effects of trimetazidine on the contractile response of chronically dysfunctional myocardium to low-dose dobutamine in ischaemic cardiomyopathy[J].Eur Heart J,2001,22(23):2164-2710.
  • 7Lu C,Dabrowski P,Fragasso G,et al.Effects of trimetazidine on ischemic leftventricular dysfunction in patients with coronary artery disease[J].Am J Cardiol,1998,82(7):898-901.
  • 8李焕德,卢安瑛,刘世坤.临床实用新药[M].3版.北京:人民卫生出版社,2006:271.
  • 9Braunwald E, Antman EM, Beasley JW, et al. ACC/AHA 2002 guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction-summary article: a report of the American College of Cardiology/American Heart Association task force on practice guidelines(Committee on the Management of Patients With Unstable Angina). J Am Coll Cardiol,2002, 40(7) :1366-1374.
  • 10Bertrand ME, Simoons ML, Fox KA, et al. Management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J,2002,23 ( 23 ) : 1809 -1840.

共引文献2131

同被引文献27

引证文献4

二级引证文献12

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部