湿化高流量双鼻导管吸氧与鼻塞持续气道正压通气对呼吸暂停早产儿鼻部损伤的影响

Comparison of nasal damage in premature infant with apnea undergoing oxygen inhalation therapy by humidified high flow nasal cannula and nasal continuous positive airway pressure

目的比较湿化高流量双鼻导管吸氧(HHFNC)与鼻塞持续气道正压通气(NCPAP)在早产儿呼吸暂停治疗过程中对鼻部的损伤程度。方法 65例呼吸暂停早产儿随机分为HHFNC组(n=32)和NCPAP组(n=33),2组均行常规护理,HHFNC组采用HHFNC治疗,NCPAP组采用NCPAP治疗。观察2组鼻部损伤情况。结果除人中部位,HHFNC组鼻内部左右侧、鼻外部左右侧及鼻中隔5个部位的损伤均显著低于NCPAP组(P<0.05或P<0.01)。结论 HHFNC在早产儿呼吸暂停治疗过程中对鼻部影响较少,利于患儿早日康复。

Objective To compare the nasal damage in premature infant with apnea undergo-ing oxygen inhalation therapy by humidified high flow nasal cannula （ HHFNC ） and nasal continuous positive airway pressure （NCPAP）. Methods A total of 65 premature infants diagnosed as apnea were randomly divided into HHFNC group（n =33） and NCPAP group （n= 32 ） . The ventilatory support based on 3M transparent dressings nasal protection and conventional nursing care were given in HHFNC and NCPAP. The nasal damage was evaluated and compared between two groups. Results The nasal damage score referring to right side, the left side and nasal septum in group NCPAP was higher than those in HHFNC group （ P 〈 0. 05 or P 〈 0. 01 ）. There was no significant difference in damage score of nasal middle part between two groups （ P 〉 0. 05 ） . Conclusion Appling HHFNC may lead less nasal damage in treatment of premature infant with apnea.