舒张性心力衰竭患者左房重构及心功能与CHADS2评分的相关性分析

Relationship between CHADS2 score and left atrial remodeling and cardiac function in diastolic heart failure patients

目的:探讨舒张性心力衰竭患者左房重构及心功能与CHADS2评分的相关性及临床意义。方法:选择2013-2015年住院符合舒张性心力衰竭诊断标准、基础疾病为高血压病、冠心病、糖尿病患者258例,所有患者按CHADS2评分为低危组、中危组、高危组3组。心功能以血浆脑钠肽浓度表示;应用多普勒超声心动图检测左室射血分数(LVEF)、左室舒张末内径(LVD)、左房内径(LAD)、室间隔厚度(IVSD)、左室后壁厚度(LVPWD)、E峰、A峰、E/A值多项指标,并同时测定患者血浆脑钠肽浓度。结果:随CHADS2评分增高,左房内径扩大,房颤比例升高,BNP值增高。结论:舒张性心力衰竭患者左房内径,房颤发生率及心功能与CHADS2评分有相关性。

Objective ：To investigate the clinical relationship between CHADS2 score and left atrial remodeling and cardiac function in diastolic heart failure patients. Methods ：258 cases of patients were selected, who were hospitalized from 2013 -2015 for diseases of hypertension, coronary heart disease, diabetes complied with diastolic heart failure diagnostic criteria. All the cases, based on CHADS2 rating, were divided into a low-risk group, a risk group, and a high-risk group. The cardiac function was presented with plasma brain na- triuretic peptide concentration;Doppler echocardiography was employed to detect left ventricular ejection fraction（ LVEF）, left ventricu- lar end-diastolic diameter （LVD） ,left atrial diameter（ LAD）, interventricular septum thickness （ （IVST） ,left ventricular posterior wall thickness （ LV PWT）, E peak, A peak, E/A value, and plasma brain natriuretic peptide concentration was also measured. Results： With chads2 score increased, the left atrial diameter expanded, and also the atrial fibrillation proportion as well as BNP value rose. Conclu- sion：Chads2 score is correlated with LVD,the incidence of atrial fibrillation and cardiac function of diastolic heart failure patients.