特布他林联合利巴韦林氧气雾化吸入治疗小儿肺炎的临床作用分析

The Effect Analysis of Terbutaline Combined with Ribavirin Oxygen Atomization Inhalation in the Treatment of Infantile Pneumonia

目的:分析特布他林联合利巴韦林氧气雾化吸入治疗小儿肺炎的临床作用。方法:选取本院儿科收治的小儿肺炎患者150例,随机将患儿分为治疗组和对照组,每组75例。对照组患儿给予传统治疗,抗感染、降温、止咳、平喘、吸氧等基础治疗;治疗组患儿在传统治疗的基础上,给予特布他林联合利巴韦林氧气雾化吸入治疗。治疗期间根据患儿具体症状和体征情况,记录患儿用药不良反应情况,比较两组患儿的治疗效果。结果:治疗组患儿发热、咳嗽、喘息、肺啰音消失时间均短于对照组患儿,差异均有统计学意义(P<0.05)。治疗结束后,治疗组患儿显效28例(37.3%)、总有效71例(94.7%);对照组患儿显效13例(17.3%)、总有效53例(70.7%)。治疗组患儿显效率和总有效率均明显高于对照组,差异均有统计学意义(P<0.05)。结论:病毒感染引起的小儿肺炎采用特布他林联合利巴韦林氧气雾化吸入,可舒张支气管平滑肌,改善患儿的通气功能,有效平喘,具有较强的理论基础和临床疗效,值得在临床中推广。

Objective： To analyze clinical effect of Terbutaline Combined with Ribavirin oxygen atomizing inhalation in treatment of infantile pneumonia.Method： The 150 children with infantile pneumonia in our hospital were selected and divided into treatment group and control group, each group had 75 cases.The control group was given conventional treatment, such as including anti-infection, cooling, relieve a cough, relieving asthma, and oxygen treatment. On the basis of traditional therapy, the treatment group was given Terhntaline combined with Ribavirin oxygen atomizing inhalation.The adverse drug reactions during the course of treatment according to children symptoms and signs were recorded, and therapeutic effect of two groups were compared.Result： The duration of fever, cough, wheeze, pulmonary rales of the treatment group were shorter than that of the control group, and the differences were statistically significant （P〈0.05） .After treatment, 28 cases （37.3%）were markedly effective and 71 cases （ 94.7% ） were total effective in the treatment group, while, 13 cases （ 17.3% ） were markedly effective and 53 cases （ 70.7% ） were total effective in the treatment group.The marked improvement rate and total effective rate of the treatment group were higher than that of the control group, and the differences were statistically significant （ P〈0.05 ） .Conclusion： Terbutaline combined with Ribavirin oxygen atomizing inhalation for treatment of infantile pneumonia which is caused by virus infection, can improve pulmonary relaxation, ventilation function, antiasthmatic activities, and has good theoretical basis and clinical curative effect, which is worth popularization in clinical.