摘要
目的:探讨C反应蛋白(CRP)、D-二聚体及降钙素原(PCT)对急性胰腺炎(AP)病情严重程度评估的临床价值。方法:收集2014年1月-2015年12月笔者所在医院收治的急性胰腺炎患者156例,其中轻症急性胰腺炎组81例,中度重症急性胰腺炎组39例,重症急性胰腺炎组36例,检测血清CRP、D-二聚体及降钙素原水平,进行BISAP、CTSI评分,分析CRP、D-二聚体、降钙素原与BISAP评分、CTSI评分之间的相关性。结果:血清CRP、D-二聚体及降钙素原在各组间均不相同,SAP组>MSAP组>MAP组,差异均有统计学意义(P<0.05);血清CRP、D-二聚体、降钙素原均与BISAP评分呈正相关(r值分别为0.747、0.743、0.663,P<0.05);血清CRP、D-二聚体、降钙素原均与CTSI评分呈正相关(r值分别为0.903、0.682、0.709,P<0.05)。结论:血清CRP、D-二聚体及降钙素原与急性胰腺炎严重程度呈正相关,对判断AP严重程度具有重要临床价值。
Objective: To explore the clinical value of C-reactive protein(CRP), D-dimer and procalcitonin in evaluating severity of acute panereatitis(AP).Method: The data from 156 patients with acute pancreatitis, who admitted into our hospital from January 2014 to December 2015 were collected, including mild acute pancreatitis(MAP) group(n=81), moderately severe acute panereatitis(MSAP) group(n=39) and severe acute panereatitis(SAP) group(n=36). The levels of serum C-reactive protein, D-dimer and procalcitonin were measured, the scores of BISAP and CTSI were obtained.The correlations between serum C-reactive protein, D-dimer, procaleitonin and BISAP scores, CTSI scores were analyzed.Result: The levels of serum C-reactive protein, D-dimer and proealcitonin were all significantly different in the different groups(P〈0.05).The levels of serum C-reactive protein, D-dimer and procaleitonin were all the highest in SAP group, followed by MSAP group, the lowest in MAP group.Serum C-reactive protein, D-dimer and procaleitonin were all positively correlated with BISAP scores(r=0.747, 0.743, 0.663, P〈0.05).Serum C-reactive protein, D-dimer and procalcitonin were all positively correlated with CTSI scores(r=-0.903, 0.682, 0.709, P〈0.05).Conclusion: Serum C-reactive protein, D-dimer and proealcitonin are all positively correlated with the severity of acute panereatitis, they have important clinical value in judging the severity of AP.
出处
《中外医学研究》
2016年第26期8-10,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH