苍南地区青年结直肠癌患者的临床与病理特点

The clinical and pathological characteristics of colorectal cancer in the young patients in Cangnan area

目的探讨苍南地区青年人结直肠癌临床与病理特点。方法收集经肠镜活检证实的473例结直肠癌患者病历资料,比较分析青年和中老年结直肠癌的临床与病理特点。结果 36例青年结直肠癌患者中男性25例(69.44%),青年和中老年患者的病变部位、分化程度、粘液腺癌发病及淋巴结转移情况差异均有统计学意义(P<0.05)。结论苍南地区青年人结直肠癌男性发病率高;与该地区中老年人相比,青年人结直肠癌更好发于直肠,且粘液腺癌占比高。

Objective To investigate the clinical and pathological characteristics of colorectal cancer in young patients in Cangnan. Method The clinical data of 473 cases of colorectal cancer as confirmed by colonoscopy biopsy were firstly collected. The clinical and pathological characteristic of colorectal cancer of the young people and those of the middle-aged and elderly people were then compared. Findings Of the 36 cases of young patients with colorectal cancer,25 cases（ 69. 44%） were male patients. The difference in the pathological location, differentiation degree, mucinous adenocarcinoma and lymph node metastasis of the young patients and the middle-aged and elderly patients was statistically significant（ P〈0. 05）. Conclusion The incidence rate of colorectal cancer in young men in Cangnan area is higher.Compared with the middle-aged and old patients in this area,colorectal cancer in the young people in Cangnan area is more common in the rectum. The proportion of mucinous adenocarcinoma is higher than that of the elderly patients.