期刊文献+

维拉佐酮关键中间体合成研究进展 被引量:2

The Synthesis Development of the Key Intermediate of Vilazodone
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摘要 5-(哌嗪-1-基)苯并呋喃-2-酯基或酰胺化合物是抗抑郁药维拉佐酮的关键中间体。综述了5-(哌嗪-1-基)苯并呋喃-2-酯基或酰胺化合物几种有代表性的合成路线,并通过不同的反应类型对哌嗪环的引入进行了论述。 5-(1-piperaziny)benzofuran-2-ester group or amide group compound is an important intermediate of antidepressant Vilazodone. This article summarized some representative synthetic routes of 5-(1-piperaziny)benzofuran-2- ester group or amide group compound, and discussed the different methods for introduction of piperazine ring.
作者 周露
出处 《浙江化工》 CAS 2016年第8期9-11,29,共4页 Zhejiang Chemical Industry
关键词 维拉佐酮 中间体 合成 哌嗪 Vilazodone intermediate synthesis piperazine
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参考文献12

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二级参考文献22

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