广元市体检人群中各型肝炎病毒血清学流行情况调查分析

Epidemic Investigation and Analysis of Various Types of Hepatitis Virus Serological Examination in Guangyuan

[目的]调查和分析广元市体检人群中各型肝炎病毒血清学流行情况。[方法]回顾性分析2011～2015年在本院健康体检的甲型肝炎病毒（HAV）、乙型肝炎病毒（HBV）、丙型肝炎病毒（HCV）、丁型肝炎病毒（HDV）、戊型肝炎病毒（HEV）各型病毒性肝炎的血清学数据，分析和比较各年间各型肝炎病毒抗体和乙肝表面抗原（HBsAg）阳性率的差异。[结果]2011～2015年HAVIgM抗体阳性率为0．17％（2／1197），HBsAg阳性率为2．89％（1722／59569）；HAVIgG抗体阳性率为0．97％（335／34628）；HDVIgM抗体阳性率为0．11％（1／948）；HEVIgM抗体阳性率为4．14％（41／991）。2011～2015年HBsAg检测阳性率分别为3．40％，3．03％，2．88％，2．66％，2．58％，各年间相比较差异具有显著性（χ2=17．385，P〈0．01）。HAVIgG抗体检测阳性率分别为1．47％，1．12％，0．86％，0．89％，0．74％，各年间比较差异亦有显著性（χ2=19．853，Pd0．01）。[结论]广元市体检人群中乙肝和丙肝的检测阳性率较高，且呈逐年下降的趋势。

[ObjectivelEpidemic investigation and analysis of various type of hepatitis virus serological examination in the Guangyuan region. [Methods]A retrospective analysis of various types of hepatitis （HAV, HBV, HCV, HDV and HEV） viral seroIogical examination data in our hospital from the years 2011-2015 was conducted. Further HAVIgM an- tibody, HBsAg, HAVIgG antibody, HDVIgM antibody, and HEVIgM and HEVIgE antibody positive rate were ana- lyzed and compared. [Results]A total of 1197 cases were detected with HAVIgM antibody from the years 2011-2015. And only 2 cases were positive; the HAVIgM positive rate was 0.17%. A total of 59596 cases were detected with HBsAg from the years 2011- 2015; 1722 cases were detected as HBsAg positive and the positive rate was 2.89 %. HBsAg posi- tive rates from the years 2011-2015 were 3.40%, 3.03%, 2.88%, 2.66%, and 2.58%; the difference between HBsAg positive detection rate had statistical significance （？（2 = 17.385, P = 0.002）. A total of 34628 cases were detected with HAVIgG antibody from the years 2011-2015; 355 cases were HAVIgG antibody positive and the positive rate was 0.97%. HAVIgG antibody positive rates from the years 2011-2015 were 1.47%, 1.12%, 0.86%, 0.89%, and 0.74% ; the difference between HBsAg positive detection rate had statistical significance （χ2 = 19.853, P =0.001）. A total of 991 cases were detected with HEVIgM antibody from the years 2011- 2015; 2 ease were positive and the positive rate was 0.20~. A total of 41 case were HEVIgM antibody positive and the positive rate was 4.14%.[Conclusion]The positive de tection rate of hepatitis B virus and hepatitis C virus of physical examination crowd was higher in Guangyuan region; but the trend declined year by year.