脑梗死合并2型糖尿病颅内外动脉粥样硬化性狭窄的分布特征

Distribution Characteristics of Intracranial Atherosclerotic Stenosis in Patients with Cerebral In- farction Complicated with Type 2 Diabetes Mellitus

[目的]探讨脑梗死合并2型糖尿病（T2DM）颅内外动脉粥样硬化性狭窄的分布特征。[方法]选取2011年12月至2015年12月本院收治的脑梗死合并T2DM患者217例，分析所有患者的一般资料及颅内外粥样硬化狭窄分布、病变血管部位及狭窄程度等。[结果]217例患者中，男性占66．8％（145／217），显著高于女性33．2％（72／217），（χ2=49．115，P〈0．05）；男性患者年龄明显小于女性（P〈0．05）；仅前循环狭窄患者占49．3％，仅后循环狭窄占22．1％，前后循环均狭窄占28．6％。217例患者颅内外动脉狭窄或闭塞513处，其中轻度狭窄184处、中度狭窄118处、重度狭窄137处、动脉闭塞74处。大脑前动脉和颈总动脉狭窄或闭塞发生率最高。前循环动脉狭窄或闭塞发生率为73．1％（375／513），高于后循环动脉狭窄或闭塞26．9％，（138／513）（χ2=218．982，P〈0．05）；颅内动脉狭窄或闭塞发生率为65．3％（335／513），高于颅外动脉狭窄或闭塞34．7％（178／513）（χ2=96．097，P〈0．001）。[结论]脑梗死合并T2DM患者颅内外动脉粥样硬化性狭窄具有一定的分布特征。

[Objective] To explore the distribution characteristics of intracranial atherosclerotic stenosis in patients with cerebral infarction complicated with type 2 diabetes mellitus. [Methods] Two hundred and seventeen patients with cerebral infarction complicated with type 2 diabetes mellitus in our hospital were selected from De- cember 2011 to December 2015. The general data of all patients , the distribution of intracranial atherosclerotic stenosis, the position of lesion blood vessels and the degree of stenosis were analyzed. [Results] In 217 patients, the male accounted for 66.8 % （ 145/217 ）, significantly higher than that of the female （ 33.2 %, 72/217 ; χ2 = 49.115, P〈0.O01）. The age of the male group was significantly younger than that of the female group （ P〈0.05）. The anterior circulation stenosis accounted for 49.3%, the posterior circulation stenosis accounted for 22.1%, the above two （both anterior and posterior） were accounted for 28.6 %. 513 intracranial artery s tenosis or occlusion were found in 217 cases of patients： mild stenosis for 184, moderate stenosis for 118, severe stenosis for 137 and arterial occlusion for 74. The incidence of stenosis or occlusion of anterior cerebral artery and common ca- rotid artery was the highest. The incidence of anterior circulation artery stenosis or occlusion was 73.1% （375/ 513）, which was higher than that of the posterior circulation artery stenosis or occlusion （26.9%, 138/513）, （χ2 =218.982, P〈0.05）;Intracranial artery stenosis or occlusion occurred in 65.3% （335/513）, higher than that of extracranial artery stenosis or occlusion 34.7% （178/513）, （χ2 = 96.097, P d0.001）.[Conclusion]Intracranial atherosclerotic stenosis in patients of cerebral infarction complicated with type 2 diabetes mellitus has a certain distribution characteristics.